Financial Times
Arts and Weekend/Fashion and Beauty section
January 9, 2004

Do Creams Beat Botox?
Hazel Curry

“…those with the second ingredient, acetyl-hexapeptide or argeriline (its trade name) may do more. Unlike the pentapeptide, this is said to do the same as Botox — reduce muscle contraction. It’s a synthetic peptide that competes with the proteins that normally relax muscle contraction signals from the neurotransmitter acetylcholine, when we express ourselves. Unlike Botox, argireline doesn’t break this communication completely, but interferes with it.”